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. Author manuscript; available in PMC: 2020 Nov 8.
Published in final edited form as: ACS Infect Dis. 2019 Oct 24;5(11):1915–1925. doi: 10.1021/acsinfecdis.9b00245

Table 4.

Surface plasmon resonance calculations

Compound ka
(M−1s−1)
kd
(s−1)
KD
(μM)
t1/2
(s)
8 (5.62 ± 0.01) × 106 28.1 ± 0.09 5.00 ± 0.02 0.02
9 (4.56 ± 0.09) × 105 0.0106 ± 0.00002 0.0234 ± 0.0005 65.2
15 (6.00 ± 1) × 103 0.362 ± 0.002 60.0 ± 10 1.91
16 (2.55 ± 0.07) × 104 (6.49 ± 0.01) × 103 0.233 114