Table 3.
Multivariate Analysis of Risk Factors for All-Cause 30-Day Mortality
| Covariate | aHR (95% CI) | P |
|---|---|---|
| Charlson comorbidity score | 1.12 (1.06–1.18) | <.001 |
| Septic shock | 2.91 (1.81–4.70) | <.001 |
| SOFA score | 1.12 (1.07–1.18) | <.001 |
| Urinary tract source | 0.64 (0.42–0.96) | <.03 |
| CVC-associated infection | 2.19 (1.27–3.79) | .005 |
| Etiology category | ||
| CSE | Reference | |
| CRE | 1.95 (1.26–3.02) | .003 |
| Nonfermentative | 2.43 (1.59–3.73) | <.001 |
| Complicated BSI | 2.02 (1.26–3.24) | .003 |
| Source control | 0.38 (0.23–0.65) | <.001 |
| Active empiric therapy | 0.68 (0.49–0.95) | .02 |
Abbreviations: aHR, adjusted hazard ratio; BSI, bloodstream infection; CI, confidence interval; CSE, carbapenem-susceptible Enterobacteriaceae; CRE, carbapenem-resistant Enterobacteriaceae; CVC, central venous catheter; NFGN, nonfermentative Gram-negative; SOFA, sequential organ failure assessment.