Table 4.
Mobility and motor, cognitive and language development according to genotype
| Deletion | Nondeletion | Total | |
|---|---|---|---|
| N | 62 | 38 | 100 |
| Mobility score mean (SD) (n = 38)** | 1.87 (0.63) | 2.67 (0.62) | 2.29 (0.76) |
| Independent walking, n (% of genetic subgroup)*** | 25 (40) | 30 (79) | 55 |
| Age of independent walking (mean in months and SD)*** | 57.9 (29.5) | 41.1 (16.1) | 48.9 (25.2) |
| Nonambulatory at age ≥4 years, n (% of genetic subgroup)*** | 24 (39) | 2 (0.05) | 26 |
| Loss of walking | 0 | 3 | 3 |
| Crouch gait, n (% of genetic subgroup) | 15 (24) | 10 (26) | 25 |
| Bayley GM DQ (SD) (n = 67) | 16.4 (9.9) | 19.9 (12.2) | 17.6 (11.2) |
| Bayley FM DQ (SD) (n = 66) | 16.7 (13.0) | 23.01 (12.98) | 19.0 (13.6) |
| Bayley cognitive DQ (SD) (n = 48)* | 15.6 (8.3) | 23.9 (14.5) | 18.0 (11.6) |
| Bayley receptive language DQ (SD) (n = 41)** | 14.8 (9.4) | 26.9 (14.97) | 20.6 (13.5) |
Abbreviations: Bayley, Bayley scales of infant and toddler development; DQ, developmental quotient; FM, fine motor; GM, gross motor.
*
Deletion versus nondeletion p < .05.
**
Deletion versus nondeletion p < .01.
***
Deletion versus nondeletion p < .001.