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. Author manuscript; available in PMC: 2019 Dec 17.
Published in final edited form as: Mol Cancer Res. 2019 Jan 3;17(3):741–750. doi: 10.1158/1541-7786.MCR-18-0451

Figure 1: Claudin-4 expression in high grade serous ovarian cancer cells.

Figure 1:

(A) CLDN4 gene expression levels in laser capture microdissected specimens of human high grade serous ovarian tumors compared to isolated normal human ovarian surface epithelial cells [36]. Western blot analysis of claudin-4 protein levels in human patient samples of normal fallopian tube and ovarian cancer (B) as well as high grade serous ovarian tumor cell lines (C), using GAPDH as a loading control. Mean ± s.e.m., n=10 HOSE, n=10–53 HGSOC tumor specimens, n=7 other EOC subtypes, *p<0.05, ***p<0.0001.