Table 1. IC50 (µM) concentrations with single agent treatments (NCI-SRB assay).
| OVSAHO | KURAMOCHI | CAOV3 | JHOC5 | Patient #1 | Patient #2 | MCF10A | |
|---|---|---|---|---|---|---|---|
| Carboplatin | 12 ± 2.5 | 13.4 ± 1.3 | 15.1 ± 3.7 | 44.4 ± 6.6 | 14.8 ± 3.3 | 4.8 ± 0.4 | 199.5 ± 20.3 |
| Olaparib | 9.3 ± 0.2 | 10.1 ± 1.4 | 13.5 ± 0.4 | 24.2 ± 4.7 | 14.7 ± 4.2 | 13.9 ± 3.1 | 30.5 ± 12.2 |
| LY294002 | 8 ± 3.2 | 5.1 ± 0.8 | 8.4 ± 1.3 | 15.5 ± 2.9 | 5.9 ± 1.1 | 4.5 ± 1.5 | 12.4 ± 2.8 |
| Crizotinib | 6.9 ± 1.1 | 4 ± 2.5 | 4.5 ± 1.3 | 6.7 ± 0.5 | 4.2 ± 0.2 | 1.8 ± 0.6 | 4.56 ± 0.9 |
| Niraparib | 10.5 ± 0.4 | 13.3 ± 3.0 | 9 ± 2.4 | 97 ± 10.0 | N/A | 10 ± 2.2 | 78.2 ± 11.4 |
N/A, not available.