Table 3.
Associations with Diagnostic conversion
| Variable | Hazard ratio | 95% CI |
|---|---|---|
| CU to MCI: All participants | ||
| SP‐ECog | 3.21* | 1.83–6.83 |
| Self‐ECog | 3.10† | 1.57–7.80 |
| APOE+ | 1.27 | 0.80–2.44 |
| Age | 1.03 | 0.98–1.10 |
| MMSE | 1.00 | 0.85–1.25 |
| Edu | 0.90‡ | 0.85–0.97 |
| Female | 0.72 | 0.51–1.20 |
| CU to MCI: Aβ+ participants | ||
| Self‐ECog | 4.30† | 1.54–20.49 |
| SP‐ECog | 1.79 | 0.96–4.68 |
| APOE+ | 1.56 | 0.73–2.44 |
| Gender | 1.12 | 0.56–3.42 |
| Age | 1.07 | 0.99–1.21 |
| Edu | 0.96 | 0.88–1.11 |
| MMSE | 0.77 | 0.64–1.05 |
| MCI to dementia: All participants | ||
| SP‐ECog | 3.11* | 2.23–4.69 |
| APOE+ | 2.32† | 1.54–3.87 |
| Female | 1.67† | 1.16–2.65 |
| Edu | 1.06‡ | 1.00–1.14 |
| Age | 1.02 | 1.00–1.05 |
| Self‐ ECog | 0.97 | 0.76–1.34 |
| MMSE | 0.84† | 0.79–0.91 |
| MCI to dementia: Aβ+ participants | ||
| SP‐ECog | 2.49* | 1.72–4.02 |
| Female | 2.07* | 1.31–3.79 |
| APOE+ | 1.67* | 1.04–2.33 |
| Self‐ ECog | 1.16 | 0.84–1.79 |
| Edu | 1.10† | 1.02–1.21 |
| Age | 1.03 | 1.00–1.08 |
| MMSE | 0.80* | 0.75–0.89 |
Variables are listed in order of magnitude of Hazards Ratio. Edu, Education; CI, Confidence interval. Bolded values indicate significant associations, *P < 0.001, † P < 0.01, ‡ P < 0.05.