Table 4.
Between group comparisons at 16 week using latent cognitive and behavioral domains from the intention to treat population
| Outcome | Control | Lovastatin | β | 95%CI | P | d | 95%CI | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Week 0 | Week 16 | Week 0 | Week 16 | ||||||||||||
| n | M | SD | M | SD | n | M | SD | M | SD | ||||||
| Latent variable | |||||||||||||||
| EF/attention | 50 | −0.02 | 0.25 | −0.03 | 0.24 | 54 | 0.01 | 0.19 | 0.03 | 0.21 | 0.04 | −0.02 to 0.09 | 0.174 | 0.26 | −0.13 to 0.65 |
| Visuospatial | 50 | −0.02 | 0.37 | −0.08 | 0.40 | 54 | 0.04 | 0.39 | 0.04 | 0.41 | 0.07 | −0.04 to 0.17 | 0.208 | 0.24 | −0.14 to 0.63 |
| Memory | 50 | −0.03 | 0.45 | −0.07 | 0.40 | 54 | 0.03 | 0.50 | 0.07 | 0.55 | 0.11 | −0.05 to 0.27 | 0.184 | 0.26 | −0.12 to 0.65 |
| Behavior | 50 | 0.04 | 0.53 | −0.03 | 0.54 | 54 | 0.00 | 0.47 | 0.00 | 0.53 | 0.05 | −0.09 to 0.19 | 0.474 | 0.14 | −0.24 to 0.53 |
Abbreviations: EF, Executive functioning; M, Mean; SD, Standard deviation; d, Cohen’s d.