Table 1. Patients’ laboratory parameters.
| Patient 1 | Patient 2 | Patient 3 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Days from liver biopsy (day 0) | -7 | -3 | 0 | -7 | -4 | 0 | -7 | -3 | 0 |
| Ferritin (ng/mL) | 1954 | 2220 | 2807 | 343 | 606 | 765 | 3253 | 1972 | 1522 |
| White blood cells (10^3 /uL) | 7.47 | 5.54 | 5.40 | 6.47 | 4.82 | 3.45 | 5.51 | 5.85 | 5.04 |
| Neutrophils (10^3 /uL) | 4.22 | 2.87 | 2.73 | 2.54 | 1.77 | 1.17 | 2.24 | 2.1 | 1.88 |
| Hb (gr/dl) | 15.9 | 16.5 | 16 | 11.5 | 10.7 | 10.3 | 11.8 | 12.5 | 11.8 |
| Platelet (x10^9/L) | 218 | 205 | 213 | 243 | 143 | 179 | 170 | 247 | 239 |
| CRP (mg/dl) | 0.41 | 0.39 | 0.56 | 1.16 | 0.83 | 0.73 | 0.29 | 0.29 | NA |
| Fibrinogen (mg/dL) | 256 | 236 | 227 | 310 | 303 | 320 | 240 | 270 | NA |
| Triglycerids (mg/dL) | 149 | 178 | 187 | 147 | 118 | 122 | 158 | 223 | NA |
| LDH (U/L) | 486 | 695 | 739 | 2128 | 5799 | 2713 | 324 | 231 | NA |
| ALT (U/L) | 1776 | 2298 | 2832 | 887 | 3996 | 1921 | 1065 | 613 | 329 |
| AST (U/L) | 670 | 965 | 1153 | 702 | 3273 | 1096 | 435 | 158 | 170 |
| GammaGT (U/L) | 209 | 278 | 290 | 28 | 130 | 139 | 103 | 110 | 103 |
| IFNγ (pg/ml) | <16 | <16 | NA | 137 | 230 | NA | NA | NA | <16 |
| CXCL9 (pg/ml) | 2911 | 5954 | NA | 24836 | 30437 | NA | NA | NA | 641 |
| CXCL10 (pg/ml) | 841 | 1838 | NA | 8758 | 9799 | NA | NA | NA | 908 |
| IL-18 (pg/ml) | 787 | 1420 | NA | 3091 | 2915 | NA | NA | NA | 62000 |
| Liver CD163-positive cells | +++ | + | +++ | ||||||
| Liver CD68-positive cells | +++ | + | +++ | ||||||
| Liver CD8-positive cells | ++ | + | + | ||||||
+ Weak staining
++ moderate staining
+++ strong staining
NA, Not Available