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. 2019 Dec 17;3(4):e367–e376. doi: 10.1055/s-0039-3401002

Table 2. Postprandial variation on complete blood count after Chilean breakfast.

Parameters K 2 EDTA K 3 EDTA
Basal 1 h 2 h 4 h Basal 1 h 2 h 4 h
RBC (10 12 /L) a
(CVa = 1.05%)
4.69
[4.50–4.98]
4.69
[4.53–5.05]
4.67
[4.51–4.99]
4.66
[4.52–4.93]
4.76
[4.54–5.01]
4.73
[4.58–5.07]
4.62
[4.47–5.01]
4.60
[4.49–4.93]
p -Value 0.153 0.081 0.014 0.940 <  0.001 <  0.001
p -Value K 2 vs. K 3 0.007
RBC (10 12 /L) b
(CVa = 0.58%)
4.76
[4.55–5.47]
4.75
[4.61–5.46]
4.70
[4.56–5.39]
4.66
[4.50–5.32]
4.76
[4.53–5.45]
4.76
[4.59–5.44]
4.72
[4.53–5.33]
4.68
[4.50–5.39]
p -Value 0.780 0.012 <  0.001 1.000 0.012 0.002
p -Value K 2 vs. K 3 0.709
Retic (10 9 /L) a
(CVa = 4.07%)
85.8
[75.1–106]
91.4
[77.6–108]
87.5
[71.4–101]
95.0
[71.0–97.4]
83.9
[71.8–105]
85.4
[73.8–104]
86.2
[69.3–94.7]
87.0
[66.8–100]
p -Value 0.185 0.668 0.926 0.940 0.003 0.097
p -Value K 2 vs. K 3 0.985
Retic (10 9 /L) b
(CVa = 3.21%)
53.5
[46.8–73.0]
56.6
[46.2–69.6]
51.2
[46.4–68.8]
53.8
[46.4–72.8]
56.4
[45.1–76.3]
54.0
[47.4–72.5]
52.1
[45.8–73.0]
53.4
[45.2–69.3]
p -Value 0.103 0.438 0.426 0.330 0.209 0.116
p -Value K 2 vs. K 3 0.670
Hb (g/L) a
(CVa = 0.93%)
146
[138–157]
144
[139–154]
144
[136–154]
142
[134–152]
144
[138–153]
145
[139–156]
142
[134–153]
142
[135–152]
p -Value 0.549 0.004 < 0.001 0.699 0.002 < 0.001
p -Value K 2 vs. K 3 0.043
Hb (g/L) b
(CVa = 0.53%)
147
[140–160]
145
[142–160]
145
[139–156]
143
[140–156]
146
[142–161]
146
[142–159]
144
[138–156]
143
[139–157]
p -Value 0.406 0.042 0.006 0.875 0.008 0.002
p -Value K 2 vs. K 3 0.944
Hct (%) a
(CVa = 1.08%)
43.6
[41.8–46.4]
43.7
[42.2–46.8]
43.6
[41.3–46.9]
42.9
[41.0–45.4]
43.4
[41.8–45.9]
43.6
[41.6–46.6]
42.2
[40.4–45.6]
42.1
[40.6–44.9]
p -Value 0.038 0.018 < 0.001 0.765 0.001 < 0.001
p -Value K 2 vs. K 3 0.013
Hct (%) b
(CVa = 0.54%)
45.8
[43.8–49.7]
45.3
[44.2–49.4]
44.6
[42.5–48.6]
43.8
[41.9–47.6]
44.4
[42.7–48.6]
44.4
[43.2–48.1]
43.4
[41.4–47.2]
42.7
[41.5–47.0]
p -Value 0.683 0.003 0.001 1.000 0.002 0.001
p -Value K 2 vs. K 3 0.001
MCV (fL) a
(CVa = 0.32%)
92.8
[90.0–95.6]
92.8
[90.2–95.1]
92.2
[89.8–94.4]
91.6
[89.5–94.1]
91.5
[88.9–94.1]
91.4
[89.0–93.6]
90.9
[88.7–92.9]
90.3
[88.0–92.5]
p -Value 0.059 < 0.001 < 0.001 0.093 < 0.001 < 0.001
p -Value K 2 vs. K 3 < 0.001
MCV (fL) b
(CVa = 0.14%)
95.0
[91.1–96.9]
95.2
[91.1–96.4]
93.8
[90.3–96.0]
93.0
[90.0–95.1]
93.2
[89.4–94.6]
93.2
[89.3–94.3]
91.8
[88.4–93.8]
91.4
[88.0–93.2]
p -Value 0.306 0.004 < 0.001 0.937 0.002 0.001
p -Value K 2 vs. K 3 0.001
RDW (%) a
(CVa = 0.57%)
13.0
[12.6–13.3]
13.0
[12.5–13.3]
12.9
[12.5–13.3]
13.0
[12.4–13.2]
13.0
[12.5–13.3]
13.0
[12.4–13.3]
12.9
[12.5–13.2]
12.9
[12.4–13.2]
p -Value 0.479 0.064 0.592 0.461 0.079 0.077
p -Value K 2 vs. K 3 0.745
RDW (%) b
(CVa = 0.56%)
13.2
[12.7–13.7]
13.2
[12.8–13.6]
13.0
[12.7–13.5]
13.0
[12.7–13.5]
13.1
[12.7–13.6]
13.0
[12.8–13.5]
13.0
[12.7–13.4]
13.0
[12.5–13.4]
p -Value 0.507 0.012 0.011 0.546 0.586 0.588
p -Value K 2 vs. K 3 0.114
WBC (10 9 /L) a
(CVa = 1.66%)
6.09
[5.15–7.06]
6.20
[5.25–7.92]
6.80
[5.87–8.05]
7.12
[6.11–8.82]
6.36
[5.14–7.10]
6.44
[5.55–7.99]
6.72
[5.86–8.16]
7.18
[6.15–8.94]
p -Value 0.422 0.002 < 0.001 0.287 0.004 0.001
p -Value K 2 vs. K 3 0.179
WBC (10 9 /L) b
(CVa = 1.30%)
5.99
[4.93–6.90]
6.27
[5.54–6.71]
6.53
[6.07–7.65]
6.97
[6.50–8.51]
6.03
[4.92–6.86]
6.32
[5.56–6.64]
6.73
[6.12–7.91]
7.05
[6.46–8.43]
p -Value 0.119 0.003 < 0.001 0.194 0.001 0.001
p -Value K 2 vs. K 3 0.834
NEU (10 9 /L) a
(CVa = 2.27%)
3.45
[2.46–4.10]
3.66
[3.01–4.77]
4.12
[3.19–4.88]
4.06
[3.10–5.03]
3.52
[2.41–4.19]
3.76
[3.05–5.03]
4.18
[3.18–4.92]
4.12
[3.23–5.08]
p -Value 0.001 0.001 0.002 0.001 0.001 0.002
p -Value K 2 vs. K 3 0.023
NEU (10 9 /L) b
(CVa = 2.44%)
3.27
[2.32–3.83]
3.60
[2.82–4.08]
4.00
[3.03–4.66]
4.04
[2.94–5.16]
3.28
[2.39–3.86]
3.72
[2.90–4.17]
3.98
[2.98–4.82]
4.18
[2.88–5.15]
p -Value 0.003 0.001 0.002 0.003 0.002 < 0.001
p -Value K 2 vs. K 3 0.571
LYMP (10 9 /L) a
(CVa = 3.74%)
2.04
[1.76–2.42]
1.87
[1.45–2.20]
1.91
[1.68–2.36]
2.30
[2.03–2.78]
2.01
[1.80–2.39]
1.86
[1.43–2.22]
1.90
[1.66–2.38]
2.30
[1.97–2.83]
p -Value 0.013 0.629 < 0.001 0.016 0.906 < 0.001
p -Value K 2 vs. K 3 0.663
LYMP (10 9 /L) b
(CVa = 1.44%)
2.07
[1.76–2.32]
1.98
[1.49–2.28]
2.06
[1.83–2.50]
2.40
[2.18–2.78]
2.04
[1.80–2.39]
1.94
[1.44–2.24]
2.13
[1.86–2.52]
2.22
[2.15–2.88]
p -Value 0.132 0.543 < 0.001 0.119 0.315 < 0.001
p -Value K 2 vs. K 3 0.551
Mono (10 9 /L) a
(CVa = 6.27%)
0.34
[0.29–0.43]
0.32
[0.26–0.36]
0.36
[0.32–0.42]
0.36
[0.33–0.42]
0.36
[0.32–0.44]
0.32
[0.29–0.42]
0.36
[0.32–0.42]
0.38
[0.33–0.42]
p -Value 0.014 0.022 0.024 0.139 0.920 0.170
p -Value K 2 vs. K 3 0.217
Mono (10 9 /L) b
(CVa = 4.34%)
0.44
[0.40–0.53]
0.40
[0.34–0.47]
0.46
[0.41–0.56]
0.52
[0.42–0.57]
0.40
[0.36–0.53]
0.36
[0.32–0.47]
0.49
[0.39–0.57]
0.50
[0.39–0.59]
p -Value 0.052 0.221 0.004 0.220 0.033 0.007
p -Value K 2 vs. K 3 0.021
Eos (10 9 /L) a
(CVa = 9.10%)
0.20
[0.11–0.27]
0.18
[0.10–0.24]
0.20
[0.10–0.28]
0.22
[0.10–0.25]
0.22
[0.11–0.28]
0.20
[0.10–0.28]
0.18
[0.10–0.26]
0.20
[0.10–0.26]
p -Value 0.161 0.499 1.000 0.147 0.053 0.528
p -Value K 2 vs. K 3 0.300
Eos (10 9 /L) b
(CVa = 8.18%)
0.22
[0.11–0.32]
0.20
[0.07–0.26]
0.23
[0.07–0.28]
0.21
[0.08–0.26]
0.20
[0.10–0.30]
0.20
[0.06–2.25]
0.23
[0.06–0.29]
0.22
[0.07–0.30]
p -Value 0.248 0.550 0.683 0.184 0.476 0.753
p -Value K 2 vs. K 3 0.784
Baso (10 9 /L) a
(CVa = 15.2%)
0.04
[0.03–0.05]
0.04
[0.03–0.05]
0.04
[0.03–0.05]
0.04
[0.03–0.05]
0.04
[0.03–0.05]
0.04
[0.04–0.05]
0.04
[0.03–0.05]
0.04
[0.03–0.05]
p -Value 0.264 0.229 0.219 0.796 0.954 0.837
p -Value K 2 vs. K 3 0.209
Baso (10 9 /L) b
(CVa = 18.3%)
0.04
[0.03–0.05]
0.04
[0.03–0.04]
0.04
[0.03–0.05]
0.04
[0.03–0.06]
0.04
[0.03–0.05]
0.04
[0.03–0.06]
0.04
[0.04–0.05]
0.04
[0.03–0.05]
p -Value 0.722 0.611 0.548 0.781 0.257 0.187
p -Value K 2 vs. K 3 1.000
Luc (10 9 /L) a
(CVa = 11.5%)
0.11
[0.09–0.12]
0.09
[0.07–0.10]
0.10
[0.08–0.12]
0.13
[0.11–0.15]
0.09
[0.09–0.10]
0.08
[0.06–0.09]
0.09
[0.08–0.11]
0.12
[0.10–0.13]
p -Value 0.002 0.244 0.002 0.017 0.417 0.004
p -Value K 2 vs. K 3 0.003
IG (10 9 /L) b
(CVa = 35.1%)
0.02
[0.01–0.03]
0.02
[0.02–0.03]
0.03
[0.02–0.04]
0.02
[0.02–0.04]
0.02
[0.01–0.03]
0.02
[0.02–0.03]
0.02
[0.02–0.03]
0.02
[0.02–0.03]
p -Value 0.608 0.053 0.061 0.111 0.674 0.193
p -Value K 2 vs. K 3 0.803
PLT (10 9 /L) a
(CVa = 2.43%)
274
[240–323]
278
[247–332]
273
[246–323]
266
[253–328]
261
[245–331]
273
[247–324]
275
[245–327]
270
[253–322]
p -Value 0.002 0.057 0.016 0.100 0.332 0.093
p -Value K 2 vs. K 3 0.370
PLT (10 9 /L) b
(CVa = 0.66%)
247
[205–301]
264
[217–305]
254
[213–303]
252
[222–304]
256
[210–300]
258
[222–311]
258
[216–307]
258
[224–311]
p -Value 0.006 0.027 0.109 0.258 0.826 0.456
p -Value K 2 vs. K 3 0.051
MPV (fL) a
(CVa = 1.88%)
8.20
[7.52–9.00]
7.95
[7.42–8.68]
7.65
[7.20–8.50]
7.65
[7.02–8.65]
8.25
[7.40–8.78]
7.85
[7.35–8.75]
7.60
[7.22–8.58]
7.55
[7.02–8.48]
p -Value < 0.001 < 0.001 < 0.001 0.024 < 0.001 < 0.001
p -Value K 2 vs. K 3 0.458
MPV (fL) b
(CVa = 0.87%)
9.85
[9.08–10.8]
9.75
[8.98–10.8]
9.80
[9.08–10.8]
9.90
[9.08–10.9]
10.2
[9.28–11.0]
10.1
[9.18–11.0]
10.1
[9.40–11.0]
10.2
[9.28–11.0]
p -Value 0.784 1.000 0.064 0.436 1.000 1.000
p -Value K 2 vs. K 3 0.001

Abbreviations: Baso, basophils; CVa, analytical coefficient of variation; Eos, eosinophils; Hb, hemoglobin; Hct, hematocrit; IG, immature granulocyte; Luc, large unstained cells; LYMP, lymphocytes; MCV, mean corpuscular volume; Mono, monocytes; MPV, mean platelet volume; NEU, neutrophils; PLT, platelet count; RBC, red blood cell count; RDW, RBC distribution width; Retic, reticulocyte; WBC, white blood cell count.

a

Hematological parameter was assayed on ADIVIA 2120 (Siemens Healthcare Diagnostics Inc, Tarrytown, New York, United States).

b

Hematological parameter was assayed on Sysmex XN-1000 (Sysmex Corporation, Kobe, Japan).

Note: Results are presented as median [interquartile range]. p -Value represents the significance by Wilcoxon ranked-pairs test. Bold p -values indicate statistical significance ( p  < 0.05).