Table 2. Postprandial variation on complete blood count after Chilean breakfast.
Parameters | K 2 EDTA | K 3 EDTA | ||||||
---|---|---|---|---|---|---|---|---|
Basal | 1 h | 2 h | 4 h | Basal | 1 h | 2 h | 4 h | |
RBC (10
12
/L)
a
(CVa = 1.05%) |
4.69 [4.50–4.98] |
4.69 [4.53–5.05] |
4.67 [4.51–4.99] |
4.66 [4.52–4.93] |
4.76 [4.54–5.01] |
4.73 [4.58–5.07] |
4.62 [4.47–5.01] |
4.60 [4.49–4.93] |
p -Value | 0.153 | 0.081 | 0.014 | 0.940 | < 0.001 | < 0.001 | ||
p -Value K 2 vs. K 3 | 0.007 | |||||||
RBC (10
12
/L)
b
(CVa = 0.58%) |
4.76 [4.55–5.47] |
4.75 [4.61–5.46] |
4.70 [4.56–5.39] |
4.66 [4.50–5.32] |
4.76 [4.53–5.45] |
4.76 [4.59–5.44] |
4.72 [4.53–5.33] |
4.68 [4.50–5.39] |
p -Value | 0.780 | 0.012 | < 0.001 | 1.000 | 0.012 | 0.002 | ||
p -Value K 2 vs. K 3 | 0.709 | |||||||
Retic (10
9
/L)
a
(CVa = 4.07%) |
85.8 [75.1–106] |
91.4 [77.6–108] |
87.5 [71.4–101] |
95.0 [71.0–97.4] |
83.9 [71.8–105] |
85.4 [73.8–104] |
86.2 [69.3–94.7] |
87.0 [66.8–100] |
p -Value | 0.185 | 0.668 | 0.926 | 0.940 | 0.003 | 0.097 | ||
p -Value K 2 vs. K 3 | 0.985 | |||||||
Retic (10
9
/L)
b
(CVa = 3.21%) |
53.5 [46.8–73.0] |
56.6 [46.2–69.6] |
51.2 [46.4–68.8] |
53.8 [46.4–72.8] |
56.4 [45.1–76.3] |
54.0 [47.4–72.5] |
52.1 [45.8–73.0] |
53.4 [45.2–69.3] |
p -Value | 0.103 | 0.438 | 0.426 | 0.330 | 0.209 | 0.116 | ||
p -Value K 2 vs. K 3 | 0.670 | |||||||
Hb (g/L)
a
(CVa = 0.93%) |
146 [138–157] |
144 [139–154] |
144 [136–154] |
142 [134–152] |
144 [138–153] |
145 [139–156] |
142 [134–153] |
142 [135–152] |
p -Value | 0.549 | 0.004 | < 0.001 | 0.699 | 0.002 | < 0.001 | ||
p -Value K 2 vs. K 3 | 0.043 | |||||||
Hb (g/L)
b
(CVa = 0.53%) |
147 [140–160] |
145 [142–160] |
145 [139–156] |
143 [140–156] |
146 [142–161] |
146 [142–159] |
144 [138–156] |
143 [139–157] |
p -Value | 0.406 | 0.042 | 0.006 | 0.875 | 0.008 | 0.002 | ||
p -Value K 2 vs. K 3 | 0.944 | |||||||
Hct (%)
a
(CVa = 1.08%) |
43.6 [41.8–46.4] |
43.7 [42.2–46.8] |
43.6 [41.3–46.9] |
42.9 [41.0–45.4] |
43.4 [41.8–45.9] |
43.6 [41.6–46.6] |
42.2 [40.4–45.6] |
42.1 [40.6–44.9] |
p -Value | 0.038 | 0.018 | < 0.001 | 0.765 | 0.001 | < 0.001 | ||
p -Value K 2 vs. K 3 | 0.013 | |||||||
Hct (%)
b
(CVa = 0.54%) |
45.8 [43.8–49.7] |
45.3 [44.2–49.4] |
44.6 [42.5–48.6] |
43.8 [41.9–47.6] |
44.4 [42.7–48.6] |
44.4 [43.2–48.1] |
43.4 [41.4–47.2] |
42.7 [41.5–47.0] |
p -Value | 0.683 | 0.003 | 0.001 | 1.000 | 0.002 | 0.001 | ||
p -Value K 2 vs. K 3 | 0.001 | |||||||
MCV (fL)
a
(CVa = 0.32%) |
92.8 [90.0–95.6] |
92.8 [90.2–95.1] |
92.2 [89.8–94.4] |
91.6 [89.5–94.1] |
91.5 [88.9–94.1] |
91.4 [89.0–93.6] |
90.9 [88.7–92.9] |
90.3 [88.0–92.5] |
p -Value | 0.059 | < 0.001 | < 0.001 | 0.093 | < 0.001 | < 0.001 | ||
p -Value K 2 vs. K 3 | < 0.001 | |||||||
MCV (fL)
b
(CVa = 0.14%) |
95.0 [91.1–96.9] |
95.2 [91.1–96.4] |
93.8 [90.3–96.0] |
93.0 [90.0–95.1] |
93.2 [89.4–94.6] |
93.2 [89.3–94.3] |
91.8 [88.4–93.8] |
91.4 [88.0–93.2] |
p -Value | 0.306 | 0.004 | < 0.001 | 0.937 | 0.002 | 0.001 | ||
p -Value K 2 vs. K 3 | 0.001 | |||||||
RDW (%)
a
(CVa = 0.57%) |
13.0 [12.6–13.3] |
13.0 [12.5–13.3] |
12.9 [12.5–13.3] |
13.0 [12.4–13.2] |
13.0 [12.5–13.3] |
13.0 [12.4–13.3] |
12.9 [12.5–13.2] |
12.9 [12.4–13.2] |
p -Value | 0.479 | 0.064 | 0.592 | 0.461 | 0.079 | 0.077 | ||
p -Value K 2 vs. K 3 | 0.745 | |||||||
RDW (%)
b
(CVa = 0.56%) |
13.2 [12.7–13.7] |
13.2 [12.8–13.6] |
13.0 [12.7–13.5] |
13.0 [12.7–13.5] |
13.1 [12.7–13.6] |
13.0 [12.8–13.5] |
13.0 [12.7–13.4] |
13.0 [12.5–13.4] |
p -Value | 0.507 | 0.012 | 0.011 | 0.546 | 0.586 | 0.588 | ||
p -Value K 2 vs. K 3 | 0.114 | |||||||
WBC (10
9
/L)
a
(CVa = 1.66%) |
6.09 [5.15–7.06] |
6.20 [5.25–7.92] |
6.80 [5.87–8.05] |
7.12 [6.11–8.82] |
6.36 [5.14–7.10] |
6.44 [5.55–7.99] |
6.72 [5.86–8.16] |
7.18 [6.15–8.94] |
p -Value | 0.422 | 0.002 | < 0.001 | 0.287 | 0.004 | 0.001 | ||
p -Value K 2 vs. K 3 | 0.179 | |||||||
WBC (10
9
/L)
b
(CVa = 1.30%) |
5.99 [4.93–6.90] |
6.27 [5.54–6.71] |
6.53 [6.07–7.65] |
6.97 [6.50–8.51] |
6.03 [4.92–6.86] |
6.32 [5.56–6.64] |
6.73 [6.12–7.91] |
7.05 [6.46–8.43] |
p -Value | 0.119 | 0.003 | < 0.001 | 0.194 | 0.001 | 0.001 | ||
p -Value K 2 vs. K 3 | 0.834 | |||||||
NEU (10
9
/L)
a
(CVa = 2.27%) |
3.45 [2.46–4.10] |
3.66 [3.01–4.77] |
4.12 [3.19–4.88] |
4.06 [3.10–5.03] |
3.52 [2.41–4.19] |
3.76 [3.05–5.03] |
4.18 [3.18–4.92] |
4.12 [3.23–5.08] |
p -Value | 0.001 | 0.001 | 0.002 | 0.001 | 0.001 | 0.002 | ||
p -Value K 2 vs. K 3 | 0.023 | |||||||
NEU (10
9
/L)
b
(CVa = 2.44%) |
3.27 [2.32–3.83] |
3.60 [2.82–4.08] |
4.00 [3.03–4.66] |
4.04 [2.94–5.16] |
3.28 [2.39–3.86] |
3.72 [2.90–4.17] |
3.98 [2.98–4.82] |
4.18 [2.88–5.15] |
p -Value | 0.003 | 0.001 | 0.002 | 0.003 | 0.002 | < 0.001 | ||
p -Value K 2 vs. K 3 | 0.571 | |||||||
LYMP (10
9
/L)
a
(CVa = 3.74%) |
2.04 [1.76–2.42] |
1.87 [1.45–2.20] |
1.91 [1.68–2.36] |
2.30 [2.03–2.78] |
2.01 [1.80–2.39] |
1.86 [1.43–2.22] |
1.90 [1.66–2.38] |
2.30 [1.97–2.83] |
p -Value | 0.013 | 0.629 | < 0.001 | 0.016 | 0.906 | < 0.001 | ||
p -Value K 2 vs. K 3 | 0.663 | |||||||
LYMP (10
9
/L)
b
(CVa = 1.44%) |
2.07 [1.76–2.32] |
1.98 [1.49–2.28] |
2.06 [1.83–2.50] |
2.40 [2.18–2.78] |
2.04 [1.80–2.39] |
1.94 [1.44–2.24] |
2.13 [1.86–2.52] |
2.22 [2.15–2.88] |
p -Value | 0.132 | 0.543 | < 0.001 | 0.119 | 0.315 | < 0.001 | ||
p -Value K 2 vs. K 3 | 0.551 | |||||||
Mono (10
9
/L)
a
(CVa = 6.27%) |
0.34 [0.29–0.43] |
0.32 [0.26–0.36] |
0.36 [0.32–0.42] |
0.36 [0.33–0.42] |
0.36 [0.32–0.44] |
0.32 [0.29–0.42] |
0.36 [0.32–0.42] |
0.38 [0.33–0.42] |
p -Value | 0.014 | 0.022 | 0.024 | 0.139 | 0.920 | 0.170 | ||
p -Value K 2 vs. K 3 | 0.217 | |||||||
Mono (10
9
/L)
b
(CVa = 4.34%) |
0.44 [0.40–0.53] |
0.40 [0.34–0.47] |
0.46 [0.41–0.56] |
0.52 [0.42–0.57] |
0.40 [0.36–0.53] |
0.36 [0.32–0.47] |
0.49 [0.39–0.57] |
0.50 [0.39–0.59] |
p -Value | 0.052 | 0.221 | 0.004 | 0.220 | 0.033 | 0.007 | ||
p -Value K 2 vs. K 3 | 0.021 | |||||||
Eos (10
9
/L)
a
(CVa = 9.10%) |
0.20 [0.11–0.27] |
0.18 [0.10–0.24] |
0.20 [0.10–0.28] |
0.22 [0.10–0.25] |
0.22 [0.11–0.28] |
0.20 [0.10–0.28] |
0.18 [0.10–0.26] |
0.20 [0.10–0.26] |
p -Value | 0.161 | 0.499 | 1.000 | 0.147 | 0.053 | 0.528 | ||
p -Value K 2 vs. K 3 | 0.300 | |||||||
Eos (10
9
/L)
b
(CVa = 8.18%) |
0.22 [0.11–0.32] |
0.20 [0.07–0.26] |
0.23 [0.07–0.28] |
0.21 [0.08–0.26] |
0.20 [0.10–0.30] |
0.20 [0.06–2.25] |
0.23 [0.06–0.29] |
0.22 [0.07–0.30] |
p -Value | 0.248 | 0.550 | 0.683 | 0.184 | 0.476 | 0.753 | ||
p -Value K 2 vs. K 3 | 0.784 | |||||||
Baso (10
9
/L)
a
(CVa = 15.2%) |
0.04 [0.03–0.05] |
0.04 [0.03–0.05] |
0.04 [0.03–0.05] |
0.04 [0.03–0.05] |
0.04 [0.03–0.05] |
0.04 [0.04–0.05] |
0.04 [0.03–0.05] |
0.04 [0.03–0.05] |
p -Value | 0.264 | 0.229 | 0.219 | 0.796 | 0.954 | 0.837 | ||
p -Value K 2 vs. K 3 | 0.209 | |||||||
Baso (10
9
/L)
b
(CVa = 18.3%) |
0.04 [0.03–0.05] |
0.04 [0.03–0.04] |
0.04 [0.03–0.05] |
0.04 [0.03–0.06] |
0.04 [0.03–0.05] |
0.04 [0.03–0.06] |
0.04 [0.04–0.05] |
0.04 [0.03–0.05] |
p -Value | 0.722 | 0.611 | 0.548 | 0.781 | 0.257 | 0.187 | ||
p -Value K 2 vs. K 3 | 1.000 | |||||||
Luc (10
9
/L)
a
(CVa = 11.5%) |
0.11 [0.09–0.12] |
0.09 [0.07–0.10] |
0.10 [0.08–0.12] |
0.13 [0.11–0.15] |
0.09 [0.09–0.10] |
0.08 [0.06–0.09] |
0.09 [0.08–0.11] |
0.12 [0.10–0.13] |
p -Value | 0.002 | 0.244 | 0.002 | 0.017 | 0.417 | 0.004 | ||
p -Value K 2 vs. K 3 | 0.003 | |||||||
IG (10
9
/L)
b
(CVa = 35.1%) |
0.02 [0.01–0.03] |
0.02 [0.02–0.03] |
0.03 [0.02–0.04] |
0.02 [0.02–0.04] |
0.02 [0.01–0.03] |
0.02 [0.02–0.03] |
0.02 [0.02–0.03] |
0.02 [0.02–0.03] |
p -Value | 0.608 | 0.053 | 0.061 | 0.111 | 0.674 | 0.193 | ||
p -Value K 2 vs. K 3 | 0.803 | |||||||
PLT (10
9
/L)
a
(CVa = 2.43%) |
274 [240–323] |
278 [247–332] |
273 [246–323] |
266 [253–328] |
261 [245–331] |
273 [247–324] |
275 [245–327] |
270 [253–322] |
p -Value | 0.002 | 0.057 | 0.016 | 0.100 | 0.332 | 0.093 | ||
p -Value K 2 vs. K 3 | 0.370 | |||||||
PLT (10
9
/L)
b
(CVa = 0.66%) |
247 [205–301] |
264 [217–305] |
254 [213–303] |
252 [222–304] |
256 [210–300] |
258 [222–311] |
258 [216–307] |
258 [224–311] |
p -Value | 0.006 | 0.027 | 0.109 | 0.258 | 0.826 | 0.456 | ||
p -Value K 2 vs. K 3 | 0.051 | |||||||
MPV (fL)
a
(CVa = 1.88%) |
8.20 [7.52–9.00] |
7.95 [7.42–8.68] |
7.65 [7.20–8.50] |
7.65 [7.02–8.65] |
8.25 [7.40–8.78] |
7.85 [7.35–8.75] |
7.60 [7.22–8.58] |
7.55 [7.02–8.48] |
p -Value | < 0.001 | < 0.001 | < 0.001 | 0.024 | < 0.001 | < 0.001 | ||
p -Value K 2 vs. K 3 | 0.458 | |||||||
MPV (fL)
b
(CVa = 0.87%) |
9.85 [9.08–10.8] |
9.75 [8.98–10.8] |
9.80 [9.08–10.8] |
9.90 [9.08–10.9] |
10.2 [9.28–11.0] |
10.1 [9.18–11.0] |
10.1 [9.40–11.0] |
10.2 [9.28–11.0] |
p -Value | 0.784 | 1.000 | 0.064 | 0.436 | 1.000 | 1.000 | ||
p -Value K 2 vs. K 3 | 0.001 |
Abbreviations: Baso, basophils; CVa, analytical coefficient of variation; Eos, eosinophils; Hb, hemoglobin; Hct, hematocrit; IG, immature granulocyte; Luc, large unstained cells; LYMP, lymphocytes; MCV, mean corpuscular volume; Mono, monocytes; MPV, mean platelet volume; NEU, neutrophils; PLT, platelet count; RBC, red blood cell count; RDW, RBC distribution width; Retic, reticulocyte; WBC, white blood cell count.
Hematological parameter was assayed on ADIVIA 2120 (Siemens Healthcare Diagnostics Inc, Tarrytown, New York, United States).
Hematological parameter was assayed on Sysmex XN-1000 (Sysmex Corporation, Kobe, Japan).
Note: Results are presented as median [interquartile range]. p -Value represents the significance by Wilcoxon ranked-pairs test. Bold p -values indicate statistical significance ( p < 0.05).