Table 2.

Cluster size, MNI coordinates, and peak Z-score of significant clusters identified by structural and functional brain analyses

Location of maxima	Cluster size (mm3)	Peak voxel MNI coordinates			Peak Z-score
		x	y	z
Gray matter volume
Initial sample
Left insula	2480	−45	−3	−4.5	4.67
Left DLPFC	2211	−34.5	57	9	4.16
Right insula	1410	45	3	1.5	4.21
Replication sample
Left DLPFC	3807	−52.5	18	19.5	3.87
Left insula	1168	−46.5	−4.5	1.5	3.72
Right insula	1137	45	−6	9	3.57
Combined meta-analysis					FWE P-value
Left insula	7617	−45	−1.5	−7.5	≪0.01
Right insula	6369	46.5	−4.5	10.5	≪0.01
Right IPL	5991	57	−66	12	≪0.01
Left DLPFC	5457	−54	19.5	24	≪0.01
Left fusiform	3446	−55.5	−60	−16.5	0.03
Left IPL	3513	−45	−79.5	30	0.03
fMRI N-back activation					Peak Z-score
Initial sample
Right IPL	1512	60	−48	21	3.13
Replication sample
Right IPL	1539	54	−69	21	3.73
Combined meta-analysis					FWE P-value
Left visual cortex	5130	−12	−90	12	≪0.01
Right IPL	2025	57	−69	18	0.03
MEG N-back beta band desynchronization					Peak Z-score
Right IPL	7125	57.5	−47.5	37.5	3.78