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. 2019 Dec 11;7:514. doi: 10.3389/fped.2019.00514

Table 1.

Comparison of clinical characteristics between IVIG-responsive and IVIG-resistant cases.

Variable Total (n = 282) IVIG-responsive (n = 259) IVIG-resistant (n = 23) P-value
Gender (M/F) 194/88 175/84 19/4 0.136
Age, months 7.00 (4.00, 9.00) 7.00 (4.00, 9.00) 8.00 (5.00, 10.00) 0.152
cKD/iKD 145/137 132/127 13/10 0.609
No. CAL 59 (20.9%) 53 (20.5%) 6 (26.1%) 0.525
White blood cell, 109/L 14.55 (11.26, 18.85) 14.49 (11.20, 18.79) 14.71 (11.31, 22.63) 0.577
Neutrophil count, 109/L 8.42 (5.91, 11.31) 8.13 (5.56, 11.14) 9.76 (8.14, 15.78) 0.009
Lymphocyte count, 109/L 4.50 (3.06, 6.05) 4.63 (3.23, 6.16) 2.60 (1.88, 3.34) <0.001
Hemoglobin, g/L 101.02 ± 11.93 101.10 ± 11.99 100.13 ± 11.48 0.709
Platelet count, 109/L 402.00 (318.00, 513.00) 404.00 (324.00, 518.00) 324.00 (230.00, 484.00) 0.028
Mean platelet volume, fl 9.70 (9.10, 10.30) 9.70 (9.10, 10.30) 9.60 (9.30, 10.60) 0.628
NLR 1.93 (1.22, 2.90) 1.79 (1.20, 2.61) 4.86 (2.74, 6.26) <0.001
PLR 94.59 (69.86, 125.14) 91.29 (69.55, 121.59) 132.74 (87.94, 198.08) 0.006
MPVLR 2.14 (1.57, 3.24) 2.07 (1.53, 3.00) 3.64 (2.78, 5.21) <0.001
Alanine transaminase, IU/L 24.00 (15.00, 42.00) 23.00 (15.00, 40.00) 33.00 (23.00, 45.00) 0.057
Serum albumin, g/L 37.42 ± 4.42 37.68 ± 4.28 34.55 ± 5.03 0.001
Serum sodium, mmol/L 137.37 (135.50, 139.30) 137.60 (135.68, 139.40) 134.80 (133.21, 137.50) 0.001

IVIG, intravenous immunoglobulin; cKD, complete Kawasaki disease; iKD, incomplete Kawasaki disease; No. CAL, numbers of coronary artery lesions; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; MPVLR, mean platelet volume-to-lymphocyte ratio.