TABLE 2.
Downregulated genes in intracellular B. bronchiseptica.
| Locus_tag | Gene | LogFC | P-value | Description |
| O-Antigen | ||||
| BB0130 | wbmO | −1.8 | 4.6E-06 | O-Antigen biosynthesis protein |
| BB0138 | wbmG | −2.2 | 1.1E-05 | Nucleotide sugar epimerase/dehydratase |
| BB0139 | wbmF | −1.8 | 9.4E-06 | Nucleotide sugar epimerase/dehydratase |
| BB0145 | bplL | −1.8 | 3.2E-06 | Lipopolysaccharide biosynthesis protein |
| BB0146 | bplJ | −1.6 | 1.2E-05 | Membrane protein |
| Adenylate cyclase toxin | ||||
| BB0325 | cyaB | −2.9 | 3.3E-09 | Cyclolysin secretion ATP-binding protein |
| BB0326 | cyaD | −3.4 | 1.0E-08 | Membrane fusion protein (MFP) family protein |
| BB0327 | cyaE | −3.3 | 5.8E-10 | Protein CyaE |
| BB0328 | cyaX | −3.9 | 1.1E-08 | Adenylate cyclase transcriptional regulator |
| Type 3 secretion system | ||||
| BB1609 | bscF | −2.1 | 6.5E-06 | Putative type III secretion protein |
| BB1623 | bcr4 | −2.6 | 6.9E-08 | Uncharacterized protein |
| BB1624 | bscI | −2.0 | 1.3E-04 | Putative type III secretion protein |
| BB1625 | bscJ | −2.3 | 4.4E-07 | Lipoprotein |
| BB1627 | bscL | −2.5 | 1.1E-04 | Type III secretion protein |
| BB1628 | bscN | −1.9 | 5.3E-06 | Type III secretion ATP synthase |
| BB1630 | bscP | −2.8 | 4.8E-07 | Type III secretion protein |
| BB1631 | bscQ | −3.0 | 4.3E-08 | Type III secretion protein |
| BB1632 | bscR | −2.1 | 6.5E-05 | Type III secretion protein |
| BB1634 | bscT | −3.0 | 3.0E-06 | Type III secretion protein |
| BB1635 | bscU | −2.8 | 7.9E-07 | Type III secretion protein |
| BB1636 | bscW | −2.8 | 9.9E-05 | Type III secretion protein |
| BB1637 | bscC | −1.9 | 3.9E-07 | Type III secretion protein |
| Electron transport | ||||
| BB3827 | −4.6 | 6.0E-10 | Putative membrane protein | |
| BB3828 | nuoN | −3.0 | 6.9E-10 | NADH-quinone oxidoreductase subunit N |
| BB3829 | nuoM | −2.3 | 2.5E-08 | NADH-ubiquinone oxidoreductase, chain M |
| BB3830 | nuoL | −2.4 | 6.9E-10 | NADH-ubiquinone oxidoreductase, chain L |
| BB3834 | nuoH | −1.7 | 1.3E-07 | NADH-quinone oxidoreductase subunit H |
| BB3835 | nuoG | −1.9 | 3.7E-08 | NADH-quinone oxidoreductase |
| BB3836 | nuoF | −2.0 | 5.7E-09 | NADH-quinone oxidoreductase subunit F |
| Cell division | ||||
| BB4188 | −2.2 | 2.4E-08 | Uncharacterized protein | |
| BB4193 | ftsZ | −2.5 | 4.3E-10 | Cell division protein FtsZ |
| BB4194 | ftsA | −3.4 | 3.3E-09 | Cell division protein FtsA |
| BB4195 | ftsQ | −3.4 | 6.0E-09 | Cell division protein FtsQ |
| BB4196 | ddl | −3.5 | 2.1E-07 | D-alanine–D-alanine ligase |
| BB4197 | murC | −3.0 | 1.1E-08 | UDP-N-acetylmuramate–L-alanine ligase |
| BB4198 | murG | −3.6 | 8.1E-10 | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase |
| BB4199 | ftsW | −3.6 | 3.6E-08 | Cell division protein FtsW |
| BB4200 | murD | −3.0 | 5.2E-09 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase |
| BB4201 | mraY | −2.8 | 1.3E-08 | Phospho-N-acetylmuramoyl-pentapeptide-transferase |
| BB4202 | murE | −2.1 | 1.0E-09 | Multifunctional fusion protein |
logFC, log2 fold change.