TABLE 5.
Type of method | Technique | LOD | References |
Quantitative methods | Thin Layer Chromatography combined with scanner | 0.1 μg/kg B2; G2; M1, 0.2 μ/kg B1; G1; | Kamimura et al., 1985 |
High Performance Liquid Chromatography, in combination with fluorescence detector | 0.002 μg/kg | Kilicel et al., 2017 | |
Liquid Chromatography with Mass Spectrometry | 0.5 μg/kg | Sirhan et al., 2013 | |
Liquid Chromatography with tandem Mass Spectrometry | 1 μg/kg | Alsharif et al., 2019; Ouakhssase et al., 2019 | |
Ultra High Performance Liquid Chromatography with fluorescence detector | 0.02 μg/kg | Beltrán et al., 2011; Cui et al., 2017 | |
Capillary electrophoresis | 1 μg/kg 0.1 ng/g | Arroyo-Manzanares et al., 2010; Xiao et al., 2018 | |
Semi-quantitative methods | ELISA | 1 ng/l | Huybrechts, 2011 |
Lateral flow tests LFT | 5 μg/kg | Goh et al., 2014, | |
Direct fluorescence | 5 μ/kg | Wacoo et al., 2014 | |
Fluorescence polarization immunoassay | 30 ng/ml | Maragos, 2009 | |
Biosensors | 0.05 ml 0.005 μg/l | Gurban et al., 2017; Man et al., 2017 | |
Indirect methods | Spectroscopy | 4 μg/kg | Wacoo et al., 2014 |
Emerging technologies | Hyperspectral imaging | 10 μg/kg | Wang et al., 2014 |
Electronic nose | 5 μ/kg | Ottoboni et al., 2018 | |
Aptamer-based biosensors ECL | 0.1 pg/ml | Shim et al., 2014; Castillo et al., 2015; Guo et al., 2016; Jia et al., 2019; Kordasht et al., 2019; |