Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Dec 17;10:5743. doi: 10.1038/s41467-019-12917-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — Transcriptome difference revealed between macular and peripheral region. a Differentially expressed genes between the overall macular and peripheral cells. All genes detected in more than 20% of macular or peripheral cells were plotted. Macular/Peripheral DEGs by overall comparison were labeled orange. Rod DEGs and RGC DEGs were labeled as red and green boxes, respectively. b The proportion of cell-type DEGs in the overall macular-peripheral DEGs showing cell population affection on DEG detection. c Heatmap demonstrating the correlation of averaged gene expression of four major cell types (rod, MG, BC, AC) in six samples. d Demonstration of mitochondrial-electron transport-related genes showing differential expression in rod cells in the macular and peripheral region. In the box plots, bounds of the box spans from 25 to 75% percentile, center line represents median, and whiskers visualize 1.5 times inter-quartile range less than quartile 1 or 1.5 times inter-quartile range more than quartile 3 of all the data points.