Figure 5.
Biology data. (a) Ex vivo biodistribution data for selected tissues in control and etoposide-treated mice 60 min after [125I]FITI injection into SW1222 tumour-bearing mice. (b) HPLC profiles of mice plasma metabolite samples showing degradation of [125I]FITI (tR = 22.3 min). (c) SPECT/CT images of SW1222 tumour mice using [123I]FITI. Control and etoposide treated mouse after 24 h, the green circle indicates the location of the xenograft. Both animals have been injected with 5 MBq of [123I]FITI.