Table 1.
RT-PCR analysis of laminin subunit transcripts. * Indicates p < 0.05.
| Control + Tx (±SEM, n) | Mutant + Tx (±SEM, n) | p value | |
|---|---|---|---|
| Lamc1-Epi | 0.7239 ± 0.1507, n = 5 | 0.4477 ± 0.1047, n = 5 | 0.1708 |
| Lamc1-Mes | 13.12 ± 3.497, n = 9 | 2.984 ± 0.5256, n = 8 | 0.0165* |
| Lamc2-Epi | 0.3355 ± 0.08577, n = 5 | 1.329 ± 0.4057, n = 6 | 0.0570* |
| Lamc2-Mes | 2.237 ± 0.4147, n = 4 | 2.851 ± 1.042, n = 5 | 0.6348 |
| Lamc3-Epi | 0.002878 ± 0.001133, n = 2 | 0.003017 ± 0.001089, n = 2 | ND |
| Lamc3-Mes | 4.646 ± 2.199, n = 5 | 1.664 ± 1.528, n = 3 | ND |
| Lama1-Epi | ND | ND | ND |
| Lama1-Mes | 1.11 ± 0.3783, n = 4 | 1.364 ± 0.6026, n = 5 | 0.7479 |
| Lama2-Epi | 0.02868 ± 0.02555, n = 3 | 0.003025 ± 0.001197, n = 4 | ND |
| Lama2-Mes | 9.874 ± 3.751, n = 6 | 3.778 ± 1.679, n = 5 | 0.2007 |
| Lama3-Epi | 0.2167 ± 0.1197, n = 5 | 0.02989 ± 0.005951, n = 3 | ND |
| Lama3-Mes | 3.022 ± 0.667, n = 5 | 1.71 ± 0.6523, n = 5 | 0.1973 |
| Lama4-Epi | 0.05141 ± 0.01605, n = 4 | 0.4325 ± 0.4176, n = 5 | 0.4476 |
| Lama4-Mes | 25.53 ± 7.401, n = 6 | 5.337 ± 2.731, n = 5 | 0.0424* |
| Lama5-Epi | 0.6793 ± 0.1252, n = 4 | 3.544 ± 2.921, n = 5 | 0.4160 |
| Lama5-Mes | 25.81 ± 8.991, n = 6 | 20.08 ± 12.49, n = 5 | 0.7121 |
| Lamb1-Epi | 0.2012 ± 0.08824, n = 5 | 8.044 ± 7.901, n = 5 | 0.3500 |
| Lamb1-Mes | 43.77 ± 12.29, n = 6 | 28.59 ± 13.01, n = 6 | 0.4160 |
| Lamb2-Epi | 0.1696 ± 0.04572, n = 4 | 0.02179 ± 0.006419, n = 4 | 0.0186 |
| Lamb2-Mes | 21.72 ± 17.39, n = 6 | 3.335 ± 1.125, n = 5 | 0.3644 |
| Lamb3-Epi | 1.006 ± 0.1636, n = 5 | 1.952 ± 0.5264, n = 6 | 0.1494 |
| Lamb3-Mes | 1.805 ± 0.4069, n = 5 | 1.845 ± 0.233, n = 5 | 0.9332 |