Table 2.
Serum chemistry analysis. * Indicates p < 0.05.
| Control + Tx (±SEM, n) | Mutant + Tx (±SEM, n) | p value | |
|---|---|---|---|
| Alk Phos: U/L | 89.25 ± 8.240, n = 4 | 91.00 ± 16.68, n = 4 | 0.9281 |
| ALT (SGPT): U/L | 23.75 ± 1.377, n = 4 | 61.75 ± 32.44, n = 4 | 0.2862 |
| AST (SGOT): U/L | 77.25 ± 20.56, n = 4 | 132.0 ± 66.99, n = 4 | 0.4643 |
| Total Bilirubin: mg/dL | 0.1250 ± 0.0250, n = 4 | 0.1000 ± 0.0, n = 4 | 0.3559 |
| Total Protein: g/dL | 4.400 ± 0.04082, n = 4 | 3.225 ± 0.3146, n = 4 | 0.0100* |
| Globulin: g/dL | 2.025 ± 0.04787, n = 4 | 1.525 ± 0.1377, n = 4 | 0.0140* |
| BUN: mg/dL | 29.25 ± 2.136, n = 4 | 30.50 ± 3.122, n = 4 | 0.7523 |
| Creatinine: mg/dL | 0.1750 ± 0.0250, n = 4 | 0.1000 ± 0.0, n = 4 | 0.0240* |
| Cholesterol: mg/dL | 53.50 ± 4.592, n = 4 | 55.50 ± 4.113, n = 4 | 0.7566 |
| Calcium: mg/dL | 8.550 ± 0.08660, n = 4 | 8.333 ± 0.1202, n = 3 | ND |
| Phosphorus: mg/dL | 9.925 ± 0.3224, n = 4 | 8.925 ± 0.5154, n = 4 | 0.1511 |
| TCO2: mmol/L | 19.00 ± 3.028, n = 4 | 21.67 ± 3.844, n = 3 | ND |
| Chloride: mmol/L | 116.5 ± 0.9574, n = 4 | 120.3 ± 2.016, n = 4 | 0.1438 |
| Potassium: mmol/L | 4.200 ± 0.3416, n = 4 | 5.125 ± 0.4366, n = 4 | 0.1462 |
| Sodium: mmol/L | 149.5 ± 1.190, n = 4 | 153.0 ± 2.041, n = 4 | 0.1891 |