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. 2019 Dec 17;9:19291. doi: 10.1038/s41598-019-55132-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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hiNPC primed with EI-tPA enhance motor recovery in T3SCI after four months. (a) BBB scores in rats grafted with hiNPC (yellow) or EI-tPA-treated hiNPC (green) or vehicle (no cell control) (blue) after T3SCI (**P < 0.01 by repeated measures ANOVA followed by Bonferroni post-hoc test, mean ± S.E.M; n = 14 animals). (b) Body weights in rats grafted with vehicle (no cell control) (blue), hiNPC (yellow), or EI-tPA-treated hiNPC (green) after T3SCI (*P < 0.05 by one-way ANOVA and Tukey's post-hoc test, mean ± S.E.M; n = 18 animals). (c) Tibialis anterior muscle weight in rats grafted with vehicle (no cell control) (blue), hiNPC (yellow) or EI-tPA-treated hiNPC (green) after T3SCI (**P < 0.01; ***P < 0.001 by one-way ANOVA and Tukey's post-hoc test, mean ± S.E.M; n = 18 animals).