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. 2019 Dec 17;9:19225. doi: 10.1038/s41598-019-52267-6

Figure 6.

Figure 6

Effect of CORT treatment on systemic responses. Birds were administered standard drinking water (CON treatment), 0.2% ethanol drinking water (ECC treatment), 10 mg/L of CORT (LD-C treatment), or 30 mg/L of CORT (HD-C treatment); birds were euthanized and sampled at 1, 5, or 12 days post-CORT administration. (AC) Total histopathologic change scores for bursa of Fabricius for (A) 1 day, (B) 5 days, or (C) 12 days post-CORT administration. (DI) Relative mRNA gene expression in (DF) liver and (GI) bursa of Fabricius. (D) SAA1. (E) CP. (F) TF. (G) IL6. (H) TGFβ2. (I) IL1β. Vertical lines associated with histogram bars represent standard error of the means (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.