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. 2019 Dec 17;9:19247. doi: 10.1038/s41598-019-55643-4

Figure 2.

Figure 2

Effects of FGF21 on blood pressure. Arterial pressure was monitored continuously for 48 hours using a mouse telemetry system in wild-type control mice (a), wild-type CKD mice (b), Fgf21−/− control mice (c), Fgf21−/− CKD mice (d), wild-type mice injected with the AAV8-LacZ (e), and wild-type mice injected with the AAV8-FGF21 (f). The systolic blood pressure data from 6 mice were overlapped in each group. The wild-type CKD mice (b) and wild-type mice injected with the AAV8-FGF21 (f) showed higher variability of systolic blood pressure than the other mice. The black bars indicate the nighttime (light off).