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. 2019 Dec 17;9:19255. doi: 10.1038/s41598-019-55896-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Circular map and genetic features of M. tuberculosis RUS_B0. Two outer circles show the coding sequences on plus (red) and minus (blue) strands; the third ring depicts CRISPR locus (black) and IS6110 integration sites (green) (Beijing B0/W148 specific sites indicated by asterisk); the fourth ring shows the positions of the VNTR; the fifth ring shows drug resistance genes; and the sixth ring shows the scale in the genome with the inverted regions with respect to the H37Rv genome.