Table 3.

Multivariate analysis of variables correlated with overall survival in the primary cohort.

Factor	HR (95% CI)	P-value
KPS, >70/≤70	3.48 (1.74–6.44)	<0.01
Liver metastases, no/yes	1.63 (1.32–2.53)	<0.01
Multiple-organ metastases, no/yes	1.52 (1.08–2.17)	<0.01
Number of lesions
1	Baseline	—
2 to 5	2.31 (1.42–3.33)	0.03
≥6	3.33 (2.34–5.95)	<0.01
Serum LDH, ≤245 vs. >245 IU/L	1.69 (1.22–2.66)	<0.01
Chemotherapy response
CR + PR	Baseline	—
SD	2.25 (1.42–3.09)	<0.01
PD	3.73 (2.31–6.98)	<0.01