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. 2019 Dec 17;9:19277. doi: 10.1038/s41598-019-55683-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of GIRK1 overexpression on transcriptome of MCF10A cells. Number of significantly up- or downregulated transcripts when MCF10A^eGFP are compared to MCF10A^GIRK1. Red: upregulated transcripts, green: downregulated transcripts. (A) Top nine gene ontology clusters derived by DAVID functional clustering. (B) Heat maps displaying the fold changes of expression levels of the top 50 genes of selected GO terms. IF γ: Interferon-γ response. ECM: extracellular matrix interaction. Migration: cell migration and WH: wound healing. Bottom right: color coding for the log2 fold change.