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Mean distance traveled scores (±SEM) of male and female preweanling rats pretreated with vehicle (upper graphs) or 2 × 200 mg/kg AMPT (lower graphs) and then tested after saline or ketamine (5–40 mg/kg) treatment on PD 21. The right graphs represent total distance traveled collapsed across the testing session. a = Significantly different from saline-treated rats from the same pretreatment condition; b = Significantly different from AMPT-pretreated rats given the same dose of ketamine.
