Table 1:
SATB2 Expression in Well-Differentiated Neuroendocrine Tumors and Pheochromocytoma/Paraganglioma
| Site of Origin | n | % positive (any non-zero H-score) | % at least moderate positive (H-score ≥100) | % high positive (H-score ≥200) | Mean (median) H-score, if positive | Range of positive H-scores |
|---|---|---|---|---|---|---|
| Lung | 46 | 13% | 0% | 0% | 23 (15) | 3–70 |
| Thyroid (Medullary) | 37 | 14% | 0% | 0% | 4 (2) | 1–7 |
| Stomach | 16 | 0% | 0% | 0% | NA | NA |
| Duodenum | 12 | 0% | 0% | 0% | NA | NA |
| Pancreas | 70 | 0% | 0% | 0% | NA | NA |
| Jejunoileum | 106 | 7% | 0% | 0% | 15 (8) | 3–43 |
| Appendix | 33 | 79% | 55% | 36% | 174 (168) | 15–300 |
| Rectosigmoid | 25 | 96% | 92% | 80% | 253 (285) | 57–300 |
| Pheochromocytoma | 22 | 0% | 0% | 0% | NA | NA |
| Paraganglioma | 22 | 14% | 0% | 0% | 5 (5) | 3–7 |