Table 1:
Strains | iCFU | Final CFU | Strains generation number | Generation time (h) of strains | Mean±SD |
---|---|---|---|---|---|
Individual cultures of strains | |||||
H | 1.5×108 | 11.27×108 | 2.907 | 115.6 | |
T | 1.5×108 | 9.65×108 | 2.69 | 124.9 | 133.34±8.44 |
Tm | 1.5×108 | 7.75×108 | 2.37 | 141.78 | |
B | 1.5×108 | 36.325×108 | 4.60 | 73.04 | 74.7±1.66 |
Bm | 1.5×108 | 31.75×108 | 4.40 | 76.36 | |
Cocultures of strains | |||||
HTm | 1.5×108 | 8.9×108 | 2.57 | 130.73 | 163. 04±32.31 |
Tm | 1.5×108 | 4.95×108 | 1.72 | 195.35 | |
HBm | 1.5×108 | 27.27×108 | 4.18 | 80.38 | 89. 31±8. 93 |
Rif + HBm | 1.5×108 | 16×108 | 3.42 | 98.24 | |
TTm | 1.5×108 | 6.68×108 | 2.16 | 155.6 | 173.8±18.2 |
Rif + TTm | 1.5×108 | 5.05×108 | 1.75 | 192 | |
TBm | 1.5×108 | 11.075×108 | 2.88 | 116.7 | 99.525±17.17 |
Rif + TBm | 1.5×108 | 25.3×108 | 4.08 | 82.35 | |
BTm | 1.5×108 | 18.3×108 | 3.61 | 93.08 | 103.295±10.22 |
Rif + BTm | 1.5×108 | 11.7×108 | 2.96 | 113.51 | |
BBm | 1.5×108 | 20.025×108 | 3.74 | 89.84 | 90.695±0.86 |
Rif + BBm | 1.5×108 | 19.10×108 | 3.67 | 91.55 |
H: Drug susceptible H37Rv strain (in individual culture), T: Drug susceptible T1 strain in individual culture, B: Drug susceptible Beijing strain (in individual culture), Tm: Drug Beijing resistant T1 strain (in individual culture), Bm: Drug Beijing resistant Beijing strain (in individual culture), HTm: Drug susceptible H37Rv strain from the competition between H37Rv and Tm strains, HBm: Drug susceptible H37Rv from the competition between H37Rv and Bm strains, TTm: Drug susceptible T1 strain from the competition between T1 and Tm strains, TBm: Drug susceptible T1 strain from the competition between H37Rv and Bm strains, BTm: Drug susceptible Beijing strain from the competition between B and drug resistant Tm strains, BBm: Drug susceptible Beijing strain from the competition between B and Bm strains, Rif + HTm: Drug resistant T1 strain from the competition between H37Rv and Tm strains on selective media, Rif + HBm: Drug resistant Beijing strain from the competition between H37Rv and Bm strains on selective media, Rif + TTm: Drug resistant T1 strain from the competition between T and Tm strains on selective media, Rif + TBm: Drug resistant Beijing strain from the competition between T and Bm strains on selective media, Rif + BTm: Drug resistant T1 strain from the competition between B and Tm strains on selective media, Rif + BBm: Drug resistant Beijing strain from the competition between B and Bm strains on selective media