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In separate group of mice (C57BL/6), mesenteric resistance and thoracic aorta blood vessels were harvested following bolus i.p. administration of vehicle control or sodium nitrite (1, or 10 mg/kg) in WT mice (C57BL/6) for 1 or 24 h. Hydrogen peroxide (H2O2) levels were measured in (A) mesenteric resistance vessels (n = 5–8) and (B) thoracic aorta (n = 7–9). Data are expressed as mean ± S.E.M. *P ≤ 0.05 as determined by one-way ANOVA with Dunnett’s test.
