Anaplerotic nodes of M. leprae versus M. tuberculosis (Mtb). Enzymes of the node are PEP carboxylase (PPC), PEP carboxykinase (PEPCK), malic enzyme (MEZ), pyruvate phosphate dikinase (PPDK), and pyruvate carboxylase (PCA). Metabolites of glycolysis, TCA cycle, and ANA (anaplerotic node) are malate (MAL), oxaloacetate (OAA), fumarate (FUM), succinate (SUC), succinyl coenzyme A (SUCCOA), 2-oxoglutarate (OXG), isocitrate (ICIT), citrate (CIT), acetyl coenzyme A (ACCOA), pyruvate (PYR), phosphoglyceric acid (PGA), glyceraldehyde-3-phosphate (GAP), fructose-6-phosphate (F6P), and glucose-6-phosphate (G6P).