Table 4.

Selected antimicrobial systems based in cationic polymers and antibiotics.

Schematic Representation of the Antimicrobial Polymer	Antibiotic	Microorganism Tested	Synergistic Effect	Ref
	Ciprofloxacin (CPF)	E. coli	Integrity of the cell membrane was disrupted by hydrophobic moieties (in an optimal concentration). CPF inhibits the activity of the bacterial DNA gyrase, which leads to bacterial cell death.	[161]
	Ciprofloxacin (CPF)	E. coli		[162]
	Polypeptide antibiotics: Polymyxin B Polymyxin R	E. coli	Combination of cationic conjugated polymers (CCPs) with polypeptide antibiotics facilitates and accelerates the rupture and collapse of bacterial membranes.	[173]
	Penicillin-G Amoxicillin Ampicillin Cefazolin	MRSA	Adsorption of metallopolymer to the negatively charged MRSA surface which promotes damage in the cell walls and at the same time allows the release of complexed antibiotic.	[169]
	Penicillin-G	E. coli P. aeruginosa P. vulgaris	Phenylboronic acid binds to peptide-glycan via boron-polyol based boronolectin chemistry, cationic cobalto-cenium moiety interact with negatively charged cell membranes and antibiotic is reinstated with enhanced vitality to attack bacteria	[170]