Differential composition of fatty acyl chains of PC-related lipid classes in plasma EVs, HDL and LDL/VLDL. Comparisons of monounsaturated fatty acid (MUFA):saturated fatty acid (SFA) ratio and polyunsaturated fatty acids (PUFA):SFA ratio in LPC (A), PC (B), and PCe (C) classes of plasma EVs, HDL, and LDL/VLDL (n = 12 per group). During analysis, PC species containing only one or >1 unsaturated bonds were classified as MUFA or PUFA, respectively. Those composed of only saturated fatty acids were classified as SFA. Relative ratios (MUFA:SFA and PUFA:SFA) were calculated for each lipid class. Statistical differences in MUFA:SFA and PUFA:SFA ratios among plasma EVs, HDL, and LDL/VLDL were examined by one-way ANOVA followed by Tukey’s test. ** p < 0.01; *** p < 0.001; **** p < 0.0001; N.S.; not significant.