Table 3.
Dose (mg/kg) | Length of Small Intestine (cm) | Distance Traveled by Charcoal Meal (cm) | Peristaltic Index (%) | % Inhibition |
---|---|---|---|---|
Control | 50.28 ± 3.05 | 38.98 ± 3.06 | 77.77 ± 5.29 | — |
80ME 100 | 53.84 ± 3.35 | 23.58 ± 5.75 | 43.87 ± 10.65 | 43.59 |
80ME 200 | 59.08 ± 2.66 | 12.00 ± 4.97b* | 21.03 ± 8.64b* | 72.96 |
80ME 400 | 56.96 ± 1.85 | 9.5 ± 4.03b* | 16.01 ± 6.84b** | 79.41 |
Loperamide 3 | 58.82 ± 2.75 | 8.6 ± 5.28b* | 14.39 ± 8.88b** | 81.5 |
a Values are given as mean ± standard error of the mean (n = 5); analysis was done using one-way analysis of variance followed by Tukey honestly significant difference (HSD) post hoc test.
b Compared with negative control values.
*P < .01, **P < .001.