Table 4.
Effects of 80% Methanol Extract (80ME) of the Leaves of Dodonaea viscosa on Gastrointestinal Fluid Accumulation in Mice.
| Dose (mg) | Volume of Intestinal Contents (mL) | % Inhibition | Weight of Intestinal Contents (g) | % Inhibition |
|---|---|---|---|---|
| Negative control | 0.86 ± 0.12 | — | 1.19 ± 0.07 | — |
| 80ME 100 | 0.36 ± 0.05b** | 58.14 | 0.58 ± 0.07b* | 51.26 |
| 80ME 200 | 0.34 ± 0.04b** | 60.47 | 0.52 ± 0.11b* | 56.30 |
| 80ME 400 | 0.30 ± 0.03b** | 65.12 | 0.51 ±0.14b* | 57.14 |
| Loperamide 3 | 0.26 ± 0.04b** | 69.77 | 0.47 ±0.11b* | 60.5 |
a Values are given as mean ± standard error of the mean (n = 5); analysis was done using one-way analysis of variance followed by Tukey honestly significant difference (HSD) post hoc test.
b Compared with negative control values.
*P < .01, **P < .001.