Table 1.
Baseline characteristics of the study cohort
| Variable | All | Subjects with major adverse cardiovascular events | Subjects without major adverse cardiovascular events | P value |
|---|---|---|---|---|
| N | 2275 | 402 | 1873 | |
| Age ≥ 65 years | 1400 (62) | 313 (78) | 1087 (58) | < 0.001 |
| Male | 1664 (73) | 270 (67) | 1394 (74) | 0.003 |
| Current smoker | 289 (13) | 49 (12) | 240 (13) | 0.73 |
| T2DM | 1617 (71) | 328 (82) | 1289 (69) | < 0.001 |
| Hypertension | 1997 (88) | 380 (95) | 1617 (86) | < 0.001 |
| BMI, kg/m2 | 25.8 ± 3.6 | 25.4 ± 3.9 | 25.8 ± 3.6 | 0.054 |
| Systolic blood pressure, mmHg | 137 ± 20 | 140 ± 23 | 137 ± 20 | < 0.001 |
| Diastolic blood pressure, mmHg | 73 ± 11 | 70 ± 12 | 74 ± 11 | < 0.001 |
| Triglycerides, mmol/L | 1.49 ± 1.02 | 1.51 ± 1.11 | 1.49 ± 1.00 | 0.65 |
| Total cholesterol, mmol/L | 3.89 ± 0.89 | 3.94 ± 1.01 | 3.88 ± 0.87 | 0.17 |
| HDL-cholesterol, mmol/L | 1.18 ± 0.33 | 1.18 ± 0.33 | 1.18 ± 0.33 | 0.79 |
| LDL-cholesterol, mmol/L | 2.01 ± 0.73 | 2.06 ± 0.83 | 2.01 ± 0.71 | 0.22 |
| HbA1c, % | 7.07 ± 1.39 | 7.41 ± 1.51 | 7.00 ± 1.36 | < 0.001 |
| Ln-hs-Tnl, pg/mL | 2.1 ± 1.2 | 2.5 ± 1.4 | 2.1 ± 1.1 | < 0.001 |
| Above cutoff (> 14.2 pg/mL) | 511 (22) | 148 (37) | 363 (19) | < 0.001 |
| Ln-BNP, pg/mL | 3.8 ± 1.1 | 4.1 ± 1.3 | 3.7 ± 1.1 | < 0.001 |
| Above cutoff (> 56.7 pg/mL) | 877 (39) | 212 (53) | 665 (36) | < 0.001 |
| Ln-Enrollment period, month | 3.1 ± 1.0 | 3.5 ± 0.9 | 3.0 ± 1.0 | < 0.001 |
Values are mean ± SD or n (%)
BMI body mass index, BNP B-type natriuretic peptide, HbA1c hemoglobin A1c, HDL-C high density lipoprotein cholesterol, hs-Tnl high-sensitivity troponin I, Ln natural logarithm, LDL-C low density lipoprotein cholesterol, T2DM type 2 diabetes mellitus