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. 2019 Dec 17;11:107. doi: 10.1186/s13195-019-0556-2

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Effect of protein vaccination on tau proteins in T5x mice. Level of human total tau protein (a, f) and several phosphorylated tau species (b–e and g–j) in brain soluble (a–e) and insoluble (f–j) extractions were analyzed by ELISA. Lines represent average (*p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; ****p ≤ 0.0001)