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Estimation of the number of clusters for methods applied to Raw counts. Boxplots of L in Eq. 1 for the subset of methods (i.e., 69 parameter combinations) that allows to estimate the number of clusters (and with none preprocessing). Superimposed as a reference, a red dashed line at L = 0. Parameter combinations with difference below or above 0 resulted into under or overestimation of the number of clusters, respectively.
