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. 2019 Dec 16;29(12):1792–1803. doi: 10.1089/thy.2019.0328

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Copyright 2019, Mary Ann Liebert, Inc., publishers

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FIG. 1. — Papillae in U-EPTC. (A, B) True papillae with fibrovascular cores (arrows) (A, H&E) in a classical PTC almost completely composed of papillae BRAF^V600E-positive by immunohistochemistry (B). (C, D) An encapsulated PTC with follicular predominant growth pattern containing occasional (<1%) papillary structures (arrows). Inset shows typical PTC nuclei (C, H&E); neoplastic cells are positive for NRAS^Q61R by immunohistochemistry (D). (E) Pseudopapillae not fulfilling the definition of true papillae since they lack fibrovascular core (arrows) (F) Pseudopapilla not fulfilling the definition of true papillae since it lacks fibrovascular core and appears to represent an artefactually ruptured septa. H&E, hematoxylin and eosin; PTC, papillary thyroid carcinoma; U-EPTC, unifocal encapsulated PTC.