Table 3. Logistic regression of factors predictive of G3/G4 adverse events.
| Variable | OR | 95% CI | p-value |
|---|---|---|---|
| Age ≥65 yr | 0.52 | 0.16–1.68 | 0.278 |
| ECOG PS ≥1 | 2.18 | 0.50–9.47 | 0.298 |
| Comorbidies number ≥3 | 6.60 | 1.87–23.36 | 0.003 |
| Creatinine serum levels ≥1.1 mg/dL | 12.68 | 2.92–55.07 | 0.001 |
| eGFR CDK-EPI <60 mL/min | 10.35 | 3.66–29.31 | 0.001 |
| Polypharmacy | 1.57 | 0.25–8.76 | 0.799 |
CI, confidence interval; ECOG PS, Eastern Cooperative Oncology Group performance status; eGFR CDK-EPI: estimated glomerular filtration rate according to Chronic Kidney Disease Epidemiology Collaboration equation; OR, odds ratio.