Figure 2.

MAPK1 is a target of miR-511. MG63 cells were randomly divided into 3 groups. Control group: normal MG63 cells; mimic NC group: MG63 cells were transfected with scramble mimics; miR-511 mimic group: MG63 cells were transfected with miR-511 mimic; The relative expressions miR-511(A) and MAPK1(B) were detected using RT-PCR in MG63 cells. $\beta$-actin was used as internal control. The experiments were repeated at least 3 times, and error bars represent $\pm$ SD (${}^{\ast }P<$ 0.05 versus Control group). (C) The luciferase activity was detected in MG63 cells transfected with mimic control, mimic, miR-511 wt and miR-511 mut. The experiments were repeated at least 3 times, and error bars represent $\pm$ SD (${}^{\ast }P<$ 0.05 versus the other 3 groups).