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. 2019 Nov 12;72(2):549–562. doi: 10.3233/JAD-190784

Table 2.

Physiological outcomes (n = 22)

Baseline Post Follow-up p p1 p2 p3
Cortisol (nmol/L)
  M1 - Upon waking 8.99 (7.46, 14.3) 12.4 (9.92, 15.8) 9.99 (7.56, 12.7) 0.057
  M2 - 30 min after waking 10.9 (9.01, 14.3) 12.6 (10.9, 16.5) 10.0 (7.88, 13.9) 0.057
  M3 - 60 min post-breakfast 8.33 (5.85, 11.3) 7.94 (6.22, 10.2) 9.59 (7.11, 12.3) 0.664
  E - 45 min post-dinner 5.45 (3.82, 6.16) 4.43 (2.81, 5.46) 4.43 (3.53, 6.94) 0.170
  M1 to E Ratio 1.35 (1.19, 1.63) 1.72 (1.54, 1.96) 1.44 (1.22, 1.79) 0.016 0.033 0.060 1.00
  M2 to E Ratio 1.45 (1.25, 1.85) 1.73 (1.58, 2.04) 1.52 (1.28, 1.80) 0.113
  AUCG 192 (146, 263) 213 (180, 258) 199 (165, 259) 0.554
Interleukin-6 (pg/mL) 29.2 (15.6, 92.8) 28.4 (15.5, 48.7) 24.8 (11.5, 68.4) 0.664

AUC, Area Under Curve. Not normally distributed variables are displayed as median (1st, 3rd quartile). Categorical variables = p1: between “Baseline” and “Post” timepoints, p2: between “Post” and “Follow-up” timepoints, p3: between “Baseline” and “Follow-up” timepoints. Outcomes were considered to be statistically significant at p < 0.05. p values for p1, p2, and p3 are corrected for the inflation of Type-I error with the Bonferroni rule.