Table 2.
Odds Ratio and 95% Confidence intervals (CI) from regression models estimating the association of 12-mo heading on the presence of low Radial Diffusivity on DTI imaging.
| BDNF Val66Met stratified analyses+ | ||||
|---|---|---|---|---|
| Met (–) playersa | Met (+) playersb | |||
| OR (95% CI) | P | OR (95% CI) | P | |
|
Heading exposure (range of heading) |
||||
| Q1 (0–174) | — | — | — | — |
| Q2 (178–548) | −0.00 (−0.73, 0.73) | 0.99 | −0.76 (−1.84, 0.32) | 0.17 |
| Q3 (556–1459) | −0.08 (−0.79, 0.63) | 0.82 | −0.89 (−2.09, 0.30) | 0.14 |
| Q4 (1460–22828) | −0.24 (−0.96, 0.48) | 0.51 | −2.36 (−3.53, −1.19) | <0.001* |
+
P-value for Met*Heading interaction from GEE model: p = 0.02.
a
Model adjusted for gender and years of education.
b
Model adjusted for gender.
*
p < 0.05.