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. Author manuscript; available in PMC: 2019 Dec 18.
Published in final edited form as: Gut. 2017 Sep 21;66(12):2043–2046. doi: 10.1136/gutjnl-2017-314744

Figure 1.

Figure 1

Effect of resistance on cure rates with two different proton pump inhibitors. First, the cure rates achieved by the studies (76% and 82%) are drawn horizontally (in green). (A) shows the results with lansoprazole based on 98% cured with all susceptible and 20% with clarithromycin resistant infections. Randomisation ensured that the proportion with resistance is similar between groups, thus the point there the cure rate crosses the 76% cure rate identifies the mean proportion with resistance for both groups. (B) Because the groups were drawn from the same population, the proportion with resistance is the same. The cure rate for the more potent PPI must cross the cure rate line (82%) at the same proportion with resistance. When extended, it shows the cure rate with resistant infections was ~40%.