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. 2019 Dec 13;68(4):1–14. doi: 10.15585/mmwr.rr6804a1

TABLE 3. Oral antimicrobial dosages for use in adults in conjunction with anthrax vaccine adsorbed for postexposure prophylaxis.

Strain Drug and dosage*
For all strains, regardless of penicillin susceptibility or if susceptibility is unknown
Ciprofloxacin, 500 mg every 12 hrs
Doxycycline, 100 mg every 12 hrs
Levofloxacin, 750 mg every 24 hrs
Moxifloxacin,§ 400 mg every 24 hrs
Clindamycin,§ 600 mg every 8 hrs
Alternatives for penicillin-susceptible strains Amoxicillin,§ 1,000 mg every 8 hrs
Penicillin VK,§ 500 mg every 6 hrs

Abbreviations: FDA = Food and Drug Administration; PEP-Abx = antimicrobial postexposure prophylaxis.

* Any one of these drug regimens.

First-line drugs; alternative drugs are listed in order of preference for PEP-Abx for patients who cannot take first-line treatment or if first-line PEP-Abx is unavailable.

§ Not FDA approved for PEP-Abx of inhalation anthrax.