TABLE 4. Antimicrobial duration when used in conjunction with Food and Drug Administration–licensed or dose-sparing postexposure prophylaxis regimens of anthrax vaccine adsorbed*.

Population with suspected or known exposure	Duration of antimicrobial regimen
Immunocompetent adults aged 18–65 yrs	42 days when initiated concurrently with first dose of AVA or for 14 days after last AVA dose, whichever is later (not to exceed 60 days)
Adults aged 18–65 yrs with immunocompromising conditions (e.g., cancer or HIV infection) or receiving immunosuppressive therapy (e.g., high-dose corticosteroids for >2 wks or radiation therapy)†	60 days
All older adults (>65 yrs)	60 days
All pregnant women and nursing mothers	60 days
All children (≤17 yrs)	60 days

  Abbreviation: AVA = anthrax vaccine adsorbed.

* If the AVA series cannot be completed, then antimicrobial therapy should continue for 60 days.

^† Source: Löbermann M, Boršo D, Hilgendorf I, Fritzsche C, Zettl UK, Reisinger EC. Immunization in the adult immunocompromised host. Autoimmun Rev 2012;11:212–8.