FIG. 1.

Effects of 5 μg BMP-2 delivery on bone formation at week 3. (A) MicroCT-measured bone volume. Comparisons among and between groups were performed by two-way ANOVA with matched pairs and Bonnferroni's multiple comparisons test. n = 4–5 per group. Each replicate is shown with summary statistics represented as mean ± SEM. ***Indicates p ≤ 0.001 versus all other groups. (B) Representative microCT images of bone formation in the defect. ANOVA, analysis of variance; BMP-2, bone morphogenetic protein-2; SEM, standard error of the mean. Color images are available online.