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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Eur J Pharm Biopharm. 2019 Oct 19;145:76–84. doi: 10.1016/j.ejpb.2019.10.007

Figure 4.

Figure 4.

Microdevices (3000 microdevices/cm2) inhibit BCRP transport in Caco-2 cells. Caco-2 cells were grown on transwell membranes for 21 days prior to measurement of prazosin transport. The values shown are the cumulative amounts of prazosin measured in the apical chamber (two-way ANOVA, Mean ± SD; ***p<0.0001 w.r.t. untreated control; n=3). Microdevices inhibit prazosin transport to a similar degree as CSA. Shown is one representative experiment of 3 independent experiments (Supporting Information 6).