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. Author manuscript; available in PMC: 2020 Nov 15.
Published in final edited form as: Neuroimage. 2019 Aug 28;202:116131. doi: 10.1016/j.neuroimage.2019.116131

Fig. 4.

Fig. 4

Conventional tractography compared with differential tractography on a multiple sclerosis patient with the first episode of optic neuritis. (a) Conventional tractography shows all existing fiber pathways in the human brain and is insensitive to any subtle decrease in the diffusion property. (b) Differential tractography ignores unaffected regions and shows the exact segments of the pathways that have a substantial decrease of anisotropy quantified between repeat scans of the same individual.