Table 2:
False Discovery Rate of Differential Tractography Findings
diagnosis | change threshold | length threshold | number of findings | false-positive findings* | FDR | |
---|---|---|---|---|---|---|
#1 | multiple sclerosis | 30% | 40 mm | 13,947 | 177 | ≤0.0126 |
#2 | multiple sclerosis | 30% | 40 mm | 2,799 | 0 | ≤0.0001 |
#3 | Huntington disease | 30% | 40 mm | 85,243 | 3,571 | ≤0.0419 |
#4 | Huntington disease | 30% | 40 mm | 64,272 | 0 | ≤0.0001 |
#5 | ALS | 15%† | 40 mm | 12,222 | 2,548 | ≤0.2085 |
#6 | epilepsy post-op | 30% | 40 mm | 15,959 | 0 | ≤0.0001 |
normal control | 30% | 40 mm | 74 |
estimated by the number of tracks with increased anisotropic diffusion
30% yields no findings