Table 1.
Study | N | Site | Treatment | Follow-up | Methods of assessment | Results |
---|---|---|---|---|---|---|
Berger et al.(2006)42 | 18 | MFC: 15 knees LFC: 7 knees IM: 2 knees BKI: 6 patients |
CD | 12 months (18 N) | MRI | All patients clinically & radiologically recovered |
Berkem et al.(2013)41 | 4 | – | CD | 14 months (1 N) | Lysholm, VAS, MRI | 1 clinically & radiologically recovered, 3 are not referred in the article |
McCarthy(1998)45 | 5 | PT: 3 patients DF: 2 patients |
CD | 2 years (3 N) | – | 3 were pain free, 2 lost on follow-up |
Karantanas et al.(2008)44 | 2 | – | CD | 2 years (2 N) | MRI | All patients were clinically & radiologically recovered |
Karantanas et al.(2008)43 | 3 | – | CD | – | – | – |
Arjonilla et al.(2004)47 | 2 | MFC: 2 patients | CD | 15.4 months (2 N) | – | In both patients symptoms resolved gradually |
Miranian et al.(2015)40 | 1 | R&L MFC, R LFC&R TP |
CD | 3 months (R knee) 9 months (L knee) |
Radiograph | Both knees had a full range of motion, no effusion, and no tenderness |
Papadopoulos et al.(2002)48 | 1 | MFC: 1 patient | CD | 3 years (1 N) | MRI | The patient was asymptomatic & no functional limitation, MRI revealed complete resolution |
Aigner et al.(2008)46 | 1 | LFC&MFC: 1 patient | CD | 9 months (1 N) | VAS | Patient became asymptomatic |
Cohen and Sharkey (2016)49 | 66 | – | SCP | 2 years (59 N-VAS) (48 N-IKDC) |
VAS, IKDC | Significant improvement in both pain and function (59 patients VAS & 48 patients IKDC) 70% nonconversion to TKA |
Farr and Cohen37 (2013) |
59 | T: 22 patients F: 15 patients KL: 22 patients MC: 48 patients LC: 8 patients MC&LC: 3 patients |
SCP | 14.7 months (59 N) | VAS, IKDC, SF-12 | Brisk pain improvement in the immediate post-operative period with a less pronounced but still progressive improvement afterwards. |
Chatterjee et al.(2015)35 | 33 | MTC: 15 patients LFC: 2 patients MFC: 5 patients |
SCP | 12 months (22 N) | KOOS, Lysholm | 12 patients-clinical success & 10 patients- clinical failure. 11 lost on follow-up |
Bonadio et al.(2016)50 | 5 | MFC: 4 patients MTP: 1 patient |
SCP | 6 months (5 N) | KOOS, VAS | Significant improvement in functional capacity & significant quick pain improvement |
Sharkey et al.(2012)54 | 1 | MTP: 1 patient | SCP | 31 months (1 N) | VAS, MRI | Early pain relief was achieved |
Fodor et al.(2016)55 | 1 | MFC: 1 patient | SCP | 1 year (1 N) | IKDC, KOOS, Lysholm | Improvement: pain, function & quality of life |
Conaway et al.(2019)51 | 1 | MTP: 1 patient | SCP | 2 years (1 N) | VAS | Continued knee pain |
Dold et al.(2017)53 | 1 | – | SCP | – | – | S. aureus osteomyelitis |
Nevalainen et al.(2015)52 | 2 | MTP: 2 patients | SCP | 17 months (1 N) 6 months (1 N) |
MRI | The pain persisted on one patient and TKA was performed 17 months after subchondroplasty on the other |
MFC = medial femoral condyle; LFC = lateral femoral condyle; IM = intraarticular migrating; BKI = bilateral knee involvement; PT = proximal tibia; DF = distal femur; TP = tibial plateau; KL = kissing lesions; MC = medial compartment; LC = lateral compartment; L = left; R = right; T = tibial; F = femoral; MTC = medial tibial condyle; MTP = medial tibial plateau; SCP = subchondroplasty; CD = core decompression; VAS = visual analogue pain scale; IKDC = international knee documentation committee; KOOS = knee injury osteoarthritis outcome score; SF-12 = 12-item short form health survey; TKA; total knee arthroplasty; N = number of patients; MRI = magnetic resonance imaging; IV = intravenous; TKA = total knee arthroplasty.