Table 1. Demographic and clinical variables comparing the second look to multiple debridements (>2 lavages).
| Second look only | Multiple debridements | ||
|---|---|---|---|
| n = 862 | n = 509 | p value* | n = 353 |
| Female sex | 142 (28%) | 0.030 | 123 (35%) |
| Age (median) | 58 years | 0.119 | 61 years |
| Immunosuppression+ | 166 (33%) | 0.754 | 126 (36%) |
| Implant infections | 192 (38%) | 0.013 | 163 (46%) |
| Bone and joint infections | 305 (60%) | 0.038 | 236 (67%) |
| Diabetic foot infections | 37 (7%) | 0.100 | 16 (5%) |
| Polymicrobial infections | 108 (21%) | 0.004 | 105 (30%) |
| Initial Gram-positive infections | 367 (72%) | 0.009 | 225 (64%) |
| Initial Gram-negative infections | 97 (19%) | 0.001 | 105 (30%) |
* Significant p values ≤0.05 are displayed in bold and italic.
+ Immunosuppression = diabetes mellitus, corticosteroid medication, organ transplantation, cirrhosis CHILD C, dialysis, cancer, untreated HIV disease, alcohol dependency, pregnancy, agranulocytosis, splenectomy