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. 2019 Dec 12;10:1271. doi: 10.3389/fgene.2019.01271

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Copyright © 2019 Chen, Ma, Xue, Zhang, Yang, Wang, Ma and Bai

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Heat map and hierarchical clustering of messenger RNA (mRNA) (A) and long non-coding RNA (lncRNA) (B) expression profiles in heart failure compared with controls. Each column represented one sample, and each row represented one mRNA or lncRNA. The relative expression levels of mRNAs and lncRNAs were depicted according to the color scale. Red indicated up-regulation and green indicated down-regulation. 2.0 and −2.0 were fold changes in the corresponding spectrum, whereas left three columns represented control samples and right three columns represented HF samples. The differentially expressed mRNAs and lncRNAs were clearly self-segregated into clusters.